- * Male or female ≥ 12 years of age; diagnosed with clinically confirmed C1-INH hereditary angioedema; experience ≥ 3 attacks during the 3 months before screening.
- Note: For subjects taking any prophylactic HAE therapy during the 3 months before Screening, ≥ 3 HAE attacks may be documented over 3 consecutive months before commencing the prophylactic therapy.
Hereditary Angioedema
CSL312 (Garadacimab) in the Prevention of Hereditary Angioedema Attacks
NCT04656418 | PHASE 3 | INTERVENTIONAL
This is a multicenter, double-blind, randomized, placebo-controlled, parallel-arm study to investigate the efficacy and safety of subcutaneous administration of CSL312 (garadacimab) in the prophylactic treatment of hereditary angioedema.
Trial Information
If interested, contact clinicaltrials@cslbehring.com for more information
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Clinical Research Center of Alabama
Birmingham,Alabama,United States,35209
Medical Research of Arizona
Scottsdale,Arizona,United States,85251
Raffi Tachdjian MD, Inc.
Santa Monica,California,United States,90404
Allergy and Asthma Clinical Research
Walnut Creek,California,United States,94598
Institute of Asthma and Allergy
Chevy Chase,Maryland,United States,20815
Bernstein Clinical Research Center LLC
Cincinnati,Ohio,United States,45231
Pennsylvania State University
Hershey,Pennsylvania,United States,17033
AARA Research Center
Dallas,Texas,United States,75231
University of Alberta Research Transition Facility
Edmonton,Alberta,Canada,T6G2B7
Ottawa Allergy Research Corp
Ottawa,Ontario,Canada,K1H1E4
Gordon Sussman Clinical Research Inc.
Toronto,Ontario,Canada,M3B3S6
Clinique specialisee en allergie de la Capitale
Québec,Canada,G1V4W2
Universittsklinikum Frankfurt GoetheUniversitt
Frankfurt,Hessen,Germany,60590
Charit Universittsmedizin Berlin
Berlin,Germany,10117
Universittsklinikum Leipzig
Leipzig,Germany,04103
CRC Clinical Research Hautklinik und Poliklinik der Universittsklinik Mainz
Mainz,Germany,55131
HZRM Hmophilie Zentrum Rhein Main GmbH
Mörfelden-Walldorf,Germany,64546
Semmelweis University
Budapest,Hungary,1088
Barzilai University Medical Center
Ashkelon,Israel,7830604
Hiroshima University Hospital
Hiroshima-shi,Hiroshima,Japan,734-8551
Kobe University Hospital
Kobe-shi,Hyogo,Japan,'650-0017
St.Marianna University School of Medicine Hospital
Kawasaki-shi,Kanagawa,Japan,216-8511
Saitama Medical Center
Saitama,Kawagoe-shi,Japan,350-8550
Saga University Hospital
Saga,Saga-shi,Japan,'849-8501
Koga Community Hospital
Yaizu-shi,Shizuoka,Japan,425-0088
Juntendo University Hospital
Bunkyo,Tokyo,Japan,113-8431
Saiyu Soka Hospital
Saitama,Japan,340-0041
Amsterdam UMC, Location AMC
Amsterdam,Netherlands,1105AZ
Study Eligibility Criteria
Additional Studies
Additional studies can be found at ClinicalTrials.gov